Anti-Hypercholesterolemia Effect of Black Rice Bran in Male Winstar Rat

Kurnia Hartati, Fadjar and Besari D, Arlin and Sigit, Bambang (2016) Anti-Hypercholesterolemia Effect of Black Rice Bran in Male Winstar Rat. In: International Food Conference 2016 INNOVATION OF FOOD TECHNOLOGY TO IMPROVEFOOD SECURITY AND HEALTH, October 20 – 21, 2016, Universitas Katolik Widya Mandala Surabaya Surabaya – Indonesia.

Preview

Text (jtpii) jurnal jtpii b fajar.pdf Download (464kB) | Preview

Abstract

This study was designed to evaluate the efficacy of Black Rice Bran (BRB) to mitigate the onset of hypercholesterolemia in Winstar rats fed with atherogenic diets. The rat was fed with the experimental diets during a 12-h period for 16 weeks. The body weights were measured every week. At the end of week-16, total of cholesterol, HDL, LDL and triacylglycerol (TAG) in their blood were measured immediately. The rats were sacrificed to remove the heart and liver, then analyzed the total cholesterol (TC) content in those organs. The rats fed with diet contained 0.5% Cholesterol and Cholic Acid exhibited more severe hypercholesterolemia than others fed with diet contained only 0.5% cholesterol. The inclusion of the BRB in the diets significantly (p < 0.05) decreased the level of TC, LDL and TAG of rats plasma fed control diets that either contained or were absent in bile salt (p < 0.05). There were no differences in HDL-level for all treatments. Conclusion: supplementation of atherogenic experimental diets with BRB decreased lipid levels for hypercholesterolemic rats, grace of bioactive components present in BRB, ex: anthocyanin, oryzanol, and fiber Keywords: Black Rice Bran; Anti-Hypercholesterolemia; Winstar Rat

Actions (login required)

View Item